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PARENTS
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OFFSPRING
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Expected average results based on at least 16 puppies.
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Both parents are NORMAL . . . not carrying the recessive gene. 100% of the offspring will be NORMAL.
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One parent is NORMAL; one parent is a CARRIER of the recessive gene . . . 50% of the offspring will be NORMAL and 50% will be CARRIERS. In PRA and RD, carriers can not be detected easily, thus pedigree analysis is critical.
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An AFFECTED parent will aslways produce CARRIER offspring. In this situation, only 50% will be AFFECTED but the other 50% will be CARRIERS. Affected individuals used for breeding automatically identify their offspring as CARRIERS.
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CARRIER to CARRIER breedings will produce 25% AFFECTED offspring, 25% NORMAL offspring, and 50% CARRIER offspring. In PRA and RD, the identification of the different offspring's genetic make-up is extremely complex.
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An AFFECTED parent will produce only AFFECTED and CARRIER offspring. AFFECTED parent bred to a NORMAL parent will not produce any AFFECTED offspring, but all will be CARRIERS.
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An AFFECTED parent bred to another AFFECTED parent will always produce 100% AFFECTED offspring.
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genetic NORMAL
genetic CARRIER
AFFECTED
